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To further determine the biological functions of this system, multi-dimensional experimental validation was conducted using cells, in vitro experiments, and in vivo evaluations on mice

Discussion 1) The results of this study completed by McCoy et al systematically evaluated the metabolic stability, BBB permeability, procognitive activity, and synaptogenic potential of Dihexa and other Nle-AngIV analogs, ultimately aiming to identify a therapeutic agent for dementia

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