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Another emerging idea is that a general 'anti-fibroblast strategy' may not suffice, and a better definition of fibroblast heterogeneity together with the specialised functions of the different subsets is needed to fine-tune potential fibroblast-based therapeutic approaches

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[8] [9] Individuals with non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH) may experience improvements as weight loss can reduce hepatic steatosis and inflammation, though tirzepatide is not licensed specifically for liver disease treatment in the UK

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