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The Nrf2/HO-1 pathway plays a vital role in antioxidative and iron-homeostatic responses, exhibiting a well-documented double-edged sword effect in ferroptosis regulation

Functional testing, where appropriate, quantifies progress more objectively

The thirty (30) cerebral glucose metabolism ROI measures, as well as the clinical measures (SF36, MFIS, MHI, and PDQ), were studied separately using linear mixed effects (LME) models with random effect of patient

As well as being a precursor to several diseases, oxidative stress is also believed to cause inflammation and contribute to visible aging

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