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33, 34 Therefore, signaling pathways able to modulate or diminish this DA increase offer enormous therapeutic potential

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Biochimica et biophysica acta 1839 , 12171225, doi: 10.1016/j.bbagrm.2014.07.013 (2014)

However, uncontrolled sun exposure can cause sunburn or local inflammation , which may aggravate existing lesions, particularly through the Koebner phenomenon, where skin trauma triggers the appearance of new patches

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