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Neo January 6, 2024, 6:52am #444 adssx: GLP1 + rapa What is your perspective on that GLP1 and also the combo with rapa would be not pro longevity in a fit, lean individual (vs rapa alone or with the other glucose regulating meds) I ask because rapa can often lead to more insulin resistance at the same time that GLP1 works via insulin up, which is NOT pro-longevity and the interaction could create even more bad signaling (not talking about in obese or overweight individuals) 2 Likes adssx January 6, 2024, 7:34am #445 I share your concerns regarding GLP-1 agonists and insulin and Im more bullish on SGLT2 specifically for this reason

Oral GLP-1 Medications Oral semaglutide now comes in two forms: Rybelsus: This is a 14 mg tablet approved for type 2 diabetes

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