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Inflammopharmacology 2013;21(3):203-211

Research shows the nasal cavity maintains a pH range of 5.5 to 6.5, and formulations must match this range to avoid irritation and peptide degradation

Transcriptomics and biochemical evidence of trigonelline ameliorating learning and memory decline in the senescence-accelerated mouse prone 8 (SAMP8) model by suppressing proinflammatory cytokines and elevating neurotransmitter release