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doi: 10.1136/annrheumdis-2016-209770 84 DaoKHBermasBL

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It is a dual-agonist, meaning it mimics two natural gut hormones: GLP-1 (Glucagon-Like Peptide-1) and GIP (Gastric Inhibitory Polypeptide)

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Thrombus formation was more pronounced in mice transplanted with bone marrow deficient in functional GLP-1R (Glp1r/) compared to those with wild-type bone marrow, with these effects being dependent on nitric oxide [57]

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