(3) improvement in adipose tissue sensitivity to lipotoxic metabolites and pro-inflammatory mediators which reduces their circulating presence
TAKANE, PhD Department of Endocrinology, University of Texas Southwestern Medical Center, Dallas Androgen Receptor Expression is Controlled by Androgens During Phallic Growth Male sexual differentiation during embryogenesis and the growth and maturation of these tissues during puberty is under the control of androgens (George and Wilson, 1994)
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Such observation could be attributed to the anti-apoptotic effect of GIP on osteoblasts (71), as osteoblast-derived hormones such as osteocalcin and lipocalcin 2 are implicated in regulating peripheral metabolism and modulate food intake (36, 72)
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Encouragement of healthy lifestyle changes: The use of this medication often motivates individuals to adopt long-term healthy habits and improve their metabolic health