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In general, patients should avoid sugary, processed foods and instead focus on balanced, nutrient-rich meals

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We propose that hepatic activation of TH signaling has insulinotropic and glucose-lowering effects, as it is able to increase non-12-OH FXR-antagonistic BA levels through shaping the BA composition by repressing hepatic CYP8B1, thereby enhancing the GLP-1 production via suppressing intestinal FXR signaling

R.Noe-LetschnigM.HandschuhP.NoeC

In summary, ferroptosis represents not merely an additional mode of cell death but a conceptual framework that links metabolic dysregulation, oxidative injury, and inflammation in cardiovascular disease