Lactose Intolerance Farmacocintica Descrio da farmacocintica das sulfonilureias de 2. gerao: Absoro: boa absoro por via oral Distribuio: ligao extensa a protenas Metabolismo: Heptico via sistema do citocromo P450 ( CYP2C9 CYP2C9 A cytochrome p-450 subtype that has specificity for acidic xenobiotics
The European Medicines Agencys (EMA) Pharmacovigilance Risk Assessment Committee concluded that no product label update was warranted, based on data from clinical trials, real-world safety monitoring, and electronic health records [45]
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Wheeler MB, Lu M, Dillon JS, Leng XH, Chen C, and Boyd AE, 3rd