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With increasing clinical studies on GLP-1 analog drugs, the bioanalytical methods for PK studies using the LC-MS/MS platform are becoming more mature
The primary mechanism of action involves several complementary pathways: Glucose-dependent insulin secretion : GLP-1 agonists stimulate pancreatic beta cells to release insulin only when blood glucose levels are elevated, reducing the risk of hypoglycaemia compared to some other diabetes medications
Published 2024 Feb 19
Studies reveal that GLP-1 medications act on the brains reward and dopamine systems, the same neural circuitry that drives addiction
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