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The studio rode the pre-Peak TV wave of scripted expansion with such distinctive hits as Mad Men, Weeds and more recently Ghosts, Yellowjackets and The Studio. But like every other studio, Lionsgates traditional profit engines are under new pressures that will challenge the leadership of a long-serving CEO

*Correspondence: Liang Guo, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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First in Human Clinical trials (FIH trials) play a critical role in bringing investigational new drugs or interventions to the clinical practice