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purity 96%), intracellular -KG levels were measured in cell lysates (10 6 cells per group) using a commercial assay kit (Sigma, MAK054-1KT) following the manufacturers instructions, as described previously 19,21

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Studies indicate that in the absence of appropriate medical intervention, approximately 20% of patients with diabetic wounds will require lower limb amputation, with a subsequent one-year mortality rate of 13% post-diagnosis 19,20

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There is no FDA-approved systemic estriol formulation for the treatment of menopausal symptoms