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Results from the phase 2 TROPION-Lung05 trial published in the Journal of Clinical Oncology revealed that among 137 patients given 6 mg/kg of dato-DXd every 21 days for pretreated NSCLC, the confirmed ORR was 35.8% (95% CI, 27.8%-44.4%), including 32.8% of patients experiencing a partial response and 2.9% having a complete response

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The early weeks are when timing alignment with meals matters mostnot for efficacy, but for symptom tolerance

[DOI] [Google Scholar] Lala D, Rabek J

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Personalization Through Genetic Testing The PlexusDx Precision Peptide Genetic Test analyzes GLP1R (rs6923761), and GIPR (rs1800437) variants that relate to GLP-1 and related signaling pathways