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Although the described findings predominantly originate from in cell line studies and animal experiments, a recent clinical study involving around 80 patients with mild cognitive impairment suggests that melatonin supplementation may also exhibit anti-tauogenic potential in humans

For HIV-associated lipodystrophy, a 2009 study found that 120 g/kg biweekly treatment showed an improvement in visceral adipose tissue by 1015% over 24 weeks, but further development was not pursued [wong (2008) abstract]

Movement and sleep amplify semaglutide's weight loss effect