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Participants who received semaglutide experienced: Significant weight reduction (average 13.7% of body weight over 68 weeks) Greater improvements in pain scores compared to placebo Enhanced physical function and mobility Reduced need for rescue analgesia These benefits appear to be likely mediated primarily through weight loss rather than any direct anti-arthritic effect of the medication
you're providing metabolic support that influences energy balance, weight management, and overall metabolic wellness
| 1 Youre not in a calorie deficit | 2 Youre in a weight-loss plateau | 3 Your current dose isnt high enough to promote lower hunger | Practical strategies | Frequently asked questions | Take home message The main reasons youre not losing weight on semaglutide (Wegovy/Ozempic) might be that youre not eating in a calorie deficit, youve hit a weight-loss plateau, or the current dose that youre on isnt high enough to lower your hunger to the point where youre eating less
Ebert, S.M
