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The AOD-9604 rabbit study specifically found that AOD-9604 combined with hyaluronic acid outperformed either treatment alone

The link between oxidation and inflammation is complex, going from fine-tuned signaling by ROS during TLR4 activation that leads to active mobilization of damaged-associated molecular patterns, to cellular injury from redox stress that leads to damaged-associated molecular patterns release triggering TLR4-mediated inflammation and organ injury (Gill et al., 2010

RELMs are believed to display inflammation-regulating, chemokine and growth-factor properties [204] and are involved in propagation of oxidative stress [211]

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While current insights suggest that they may be taken together without significant risk, individual considerations are paramount