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UBX0101, a p53/MDM2 interaction inhibitor, improves osteoarthritis by eliminating senescent synovial cells in the knee joint

The catenation of sulfur atoms endows supersulfides with unique reactivity as it positions them as critical regulators in various biological processes, such as enzyme activity, oxidative stress response, energy metabolism, pathogen infection, and immune modulation (1517) ( Figure 1 )