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Interestingly, in the same study, patients with MS with prolonged recorded somatosensory evoked potentials and prolonged visual evoked potentials had decreased B12 levels compared to patients with normal recorded values [121]

Cost considerations favor oral supplements : IV therapy runs $199-$400+ per session with typical protocols requiring 1-3 sessions weekly ($800-$4800+ monthly), whereas oral supplements offer a more budget-friendly option with the convenience of home administration

Adenosylcobalamin is the form of vitamin B12 associated most closely with improving energy levels

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Multiple daily administrations needed

An intradermal test dose is recommended before cyanocobalamin injection is administered to patients suspected of being sensitive to this drug