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Finally, the activation of NOX2 and NOX4 alters the pH of the medium, which may further favor the formation of senile plaques from A aggregates [18,19]

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Biol Trace Elem Res 155(2):190200 Costarelli L, Muti E, Malavolta M, Cipriano C, Giacconi R, Tesei S, Tirabassi G (2010) Distinctive modulation of inflammatory and metabolic parameters in relation to zinc nutritional status in adult overweight/obese subjects