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The terminology is contested, but the underlying observation is not: the metabolic deterioration of neurons, their diminishing capacity to produce and manage energy, appears to be an early and potentially modifiable feature of the disease process, not merely a downstream consequence of it

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Nevertheless, analysts caution that drug manufacturing takes years to ramp up and capacity constraints will persist in the near term ( [12] ) ( [32] )

A study in the Journal of Clinical Endocrinology & Metabolism found that receptors for these medications are present in brain regions like the hypothalamus, which regulates body temperature

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