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Loss of ERalpha induces amoeboid-like migration of breast cancer cells by downregulating vinculin

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doi: 10.1016/j.semcancer.2019.03.002 45 LiuJXiaXHuangP

Moreover, further studies suggested that BPC-157 regulated the phosphorylation level of extracellular signal-regulated kinases 1 and 2 (ERK1/2) as well as its downstream targets, including c-Fos, c-Jun, and Egr-1, which are key molecules involved in cell growth, migration, and angiogenesis

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