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In such a way that unoxidized fatty acids are rerouted toward the synthesis of diacylglycerol and ceramide, which in turn stimulate stress-induced protein kinases that inhibit insulin signaling (89, 90)

Rounding 37.5 down to 37 changes the dose by about 1.3%, which is clinically irrelevant

Function of NPT4 ( SLC17A3 ) NPT4 plays an important role in the urate excretion and operates functionally with basolateral organic anion transporters 1/3 (OAT1/OAT3) (Jutabha et al., 2010

Spenciner, Alexandra R

HZ conceived and directed the idea of the manuscript