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Another study conducted the same year: Eye contour cream application on 41 women showed that GHK-Cu reduced wrinkles and increased skin density more than placebo and vitamin K creams

If redness persists for hours, spreads beyond the application area, or worsens over time, reduce concentration or frequency

The strongest evidence remains in topical applications, while injectable GHK-Cu should be viewed as an investigational compound with unknown safety profiles

What Changed in 2026 In early 2026, the government announced plans to let about 14 peptides including BPC157 and TB500 be made again by licensed pharmacies with a doctors prescription

Practical guidance: Apply GHK-Cu immediately after microneedling and continue daily for 1 to 2 weeks

Higher doses and shorter durations fit acute healing