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The efficacy and safety of setmelanotide in individuals with Bardet-Biedl syndrome or Alstrom syndrome: phase 3 trial design

The rest received the same lifestyle counseling and a placebo jab

[DOI] [PMC free article] [PubMed] [Google Scholar] [182].Vandeplas S, Dubois Dauphin R, Beckers Y, Thonart P, Thewis A

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The broader receptor profile of these newer-generation GLP-1 receptor agonists is thought to offer clinical advantages, potentially providing better tolerability or enhanced effectiveness due to simultaneous modulation of reward-related neural circuits and metabolic pathways (Ray 2023

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