On an empty GLP-1 stomach, this often triggers nausea and heartburn
P = 0.65) and cardiovascular death (0.91
It is our responsibility to realize the magnitude of this sudden change in clinical management of T2D
Specific intervention scenarios of GLP-1 on cellular energy economics Treatment of diabetes: correcting the "imbalance of energy distribution" The core pathology of type 2 diabetes is insulin resistance and beta cell function failure, which leads to the imbalance of energy distribution: the intake of glucose by muscle and adipose tissue is reduced, the liver gluconeogenesis is increased, and the levels of glucose and FFA in the blood are increased, forming a vicious cycle of "hyperglycemia hyperlipidemia"
However, the disparity in costs for obesity-specific medications underscores the pressing need for more equitable access to these therapies
Whether these additions provide meaningful benefit is debatable, but some patients report improved energy and reduced side effects with enhanced formulations